1921-22 Eastern Canada Memorial Cup Playoffs

Champions

 * Thunder Bay: Fort William War Veterans
 * Northern Ontario: Iroquois Falls Eskimos
 * Ontario: Toronto Aura Lee
 * Quebec: McGill University

Quarter Final
Sudden death


 * March 11 Toronto Aura Lee 4 Iroquois Falls Eskimos 0 @ Toronto

Semi Final
Sudden death


 * March 14 Toronto Aura Lee 9 McGill University 4 @ Toronto

Final
Sudden death


 * March 17 Fort William War Veterans 5 Toronto Aura Lee 3 @ Fort William

Fort William War Veterans advanced to the 1921-22 Memorial Cup Final.

Note: In the early 1920's the Thunder Bay champions played in the Eastern Canada playoffs in the years that the Memorial Cup final was held in the west,